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Author: Admin | 2025-04-28
HomeNaloxone Generic name: naloxone [ nah-LOX-one ]Brand names: Narcan, Rezenopy, Kloxxado, ZimhiDosage form: Injectable solution (Zimhi 5 mg/0.5 mL), Nasal spray (Narcan 4 mg, Rezenopy 10 mg, Kloxxado 8 mg)Drug class: Antidotes UsesWarningsBefore takingDosageSide effectsInteractionsFAQ What is naloxone?Naloxone is an FDA approved medicine used to quickly reverse an opioid overdose. Naloxone is a opioid antagonist that works by attaching to opioid receptors and therefore reverses and blocks the effects of other opioids. Naloxone should be used as soon as possible to treat a known or suspected opioid overdose emergency if there are signs of slowed breathing, severe sleepiness or the person is not able to respond (loss of consciousness). Once naloxone has been given the patient must receive emergency medical care straight away, even if they wake up.Naloxone is not a controlled substance, according to the US Drug Enforcement Administration (DEA).Naloxone is available as a nasal spray (Narcan 4mg, Rezenopy 10 mg, Kloxxado 8mg) or an injection (Zimhi 5 mg/0.5 mL).Narcan nasal spray became approved by the FDA on March 29, 2023 as is an over-the-counter (OTC) medicine that is available without a prescription. Other naloxone products are still prescription medicines, but in many states, these products are available from a pharmacist without a prescription from your doctor, under state Naloxone Access Laws or alternate arrangements.Opioids are sometimes called a narcotic. Examples of opioids are buprenorphine, codeine, fentanyl, oxycodone (Oxycontin), heroin, hydrocodone (Vicodin, Lortab), hydromorphone, meperidine, morphine, methadone, oxymorphone, and tramadol. What is Naloxone used for?Naloxone is used to treat a known or suspected opioid overdose emergency in children or adults. Signs of an opioid overdose may include:slowed breathing, or no breathing;very small or pinpoint pupils in the eyes;slow heartbeats; orextreme drowsiness, especially if you cannot wake the person from sleep.Even if you are not sure an opioid overdose has occurred, if the person is not breathing or is unresponsive, give the naloxone right away and then seek emergency medical care.Naloxone has different uses when used in multi-ingredient medications including buprenorphine with naloxone (Suboxone, Zubsolv, Bunavail) which is used to treat opioid addiction, and naloxone with oxycodone (Targiniq ER) which
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