Permethrin for dogs

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Author: Admin | 2025-04-28

1 quart Paramite L.A. in 25 gal of water OR 1 cup Paramite L.A. in 6.25 gal of water. Phosmet concentration in final dilution: ~1175 ppm* = mg/L = 0.1175% active ingredient.* ppm = parts per millionSAFETYLD50 (acute oral) in rats: for the a.i. 113 mg/kgLD50 (acute dermal) in rats: for the a.i. >4640 mg/kgEstimated hazard class according to the WHO: II, moderately hazardousWithholding periods (=withdrawal times) in days for meat & milk (country-specific differences may apply: read the product label)Meat:Cattle: USA: 3 daysSwine: USA 1 dayMilk for human consumption: USA Not approved for use on lactating dairy cows.WARNING !!!: Never use on humans, dogs or cats.Phosmet and all organophosphates (e.g. coumaphos, diazinon, dichlorvos, etc.) etc. are highly toxic to birds, fish and aquatic invertebrates. Do not apply directly to water, or to areas where surface water is present, or to intertidal areas below the mean high water mark. Do not contaminate water when cleaning equipment or disposing of equipment washwaters.You may be interested in the following articles in this site dealing with the general safety of veterinary products:Safety for humansSafety for domestic animalsSafety for the environmentHazard classifications of pesticidesRESISTANCE PREVENTIONRisk of resistance? YES; cases of resistance of horn flies to organophosphates have been reported in the USA and elsewhere, but resistance to organophosphates is usually weaker and less widespread than to synthetic pyrethroids (e.g. permethrin). Resistance of most tick species, lice and mites (both of cattle & swine) to organophosphates is usually not a problem in most of the USA.This means that if this product does not achieve the expected efficacy against horn flies, it may be due to resistance. However incorrect use is usually the most frequent cause of product failure.Alternative chemical classes/active ingredients to prevent resistance of external parasites through product rotation:Macrocyclic lactones (e.g. doramectin, eprinomectin, ivermectin, moxidectin, etc.) only as pour-ons. Injectables and drenches are ineffective against most external parasites.Synthetic pyrethroids (e.g. permethrin). Resistance of horn flies and many other pests to these compounds is usually stronger and more frequent than to organophosphates.These alternative products may not be available in all countries, or may not be

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