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Author: Admin | 2025-04-28
A link may exist between phentermine and heart failure. There are rare reports of valvular heart disease in people who have taken phentermine, and it may also cause pulmonary hypertension.Valvular heart disease involves damage to one or more of the valves in the heart. These valves open and close to regulate blood flow.Additionally, phentermine may cause another, equally serious, side effect: pulmonary hypertension. This is high blood pressure in the arteries of the lungs. People with cardiovascular disease or conditions affecting the heart and lungs should not take phentermine.This article discusses the association between phentermine and heart failure. It also examines who should not take the drug, other risks, and alternative help for obesity.Phentermine is a brain and spinal cord stimulant medication. It can suppress a person’s appetite, making it popular as a weight loss drug.In 1959, phentermine first came onto the market as part of a combination obesity drug. Then, in the 1980s, researchers discovered that phentermine and fenfluramine — another appetite suppressant — had a synergistic effect when a person took them together. This means their combined effect was greater than the sum of their two separate effects. At this time, the combination drug “fen-phen” became a mainstay of obesity treatment.However, fen-phen had a strong link to pulmonary hypertension and valvular heart disease. Researchers also discovered a link between fenfluramine alone and these two conditions. Consequently, the Food and Drug Administration (FDA) banned fenfluramine in 1997, but it continues to allow the short-term use of phentermine.Sometimes, doctors prescribe phentermine alone. Alternatively, they prescribe a combination drug containing topiramate, an antiseizure drug. The possibility of heart failure differs when taking phentermine alone and taking the combination drug. PhentermineExperts cannot rule out a link between phentermine alone and heart valve disease. There have been rare reports of the condition manifesting in people who took it.Combination of phentermine and topiramateThe combination of phentermine and topiramate may increase resting heart rate up to 20 beats per minute (bpm). This means that a person who normally has a resting heart rate of 75 bpm would have a resting heart rate as high as
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