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Author: Admin | 2025-04-28
For the treatment of refractory chronic cough Generalized anxiety disorderbyesData from several meta-analyses support the use of pregabalin in the treatment of generalized anxiety disorder Baldwin 2011, Boschen 2011, Generoso 2017, Lydiard 2010.Based on the Neuropathic pain, critically ill patientsyesThe Society of Critical Care Medicine Clinical Practice Guidelines for the Prevention and Management of Pain, Agitation/Sedation, Delirium, Immobility, and Sleep Disruption in Adult Patients in the ICU suggest pregabalin in combination with opioids is recommended for the management of neuropathic pain in ICU patients SCCM [Devlin 2018].Postoperative pain (as a component of multimodal analgesia in select patients)bData from several meta-analyses support the use of preemptive doses of pregabalin to decrease postoperative pain, opioid use, and nausea and vomiting Pruritus, neuropathic or malignancy relatedcData from a limited number of patients studied suggest that pregabalin may be beneficial for the treatment of chronic neuropathic or malignancy-related pruritus Pruritus, uremicbyesData from several randomized, controlled trials support the use of pregabalin in the treatment of chronic uremic pruritus in dialysis patients Foroutan 2017, Solak 2012, Yue 2015.Based on the European Dermatology Forum and European Academy of Dermatology and Venerology guidelines on chronic pruritus, pregabalin is recommended in the management of chronic kidney disease-associated pruritus Restless legs syndromebyesData from randomized, double-blind, placebo-controlled studies support the use of pregabalin in the treatment of moderate to severe primary restless legs syndrome (RLS) with predominant evening symptoms Allen 2010, Allen 2014, Garcia-Borreguero 2014.Based on American Academy of Neurology guidelines and guidelines from the International Restless Legs Syndrome Study Group for the long-term treatment of RLS, pregabalin is effective and recommended in the management of primary RLS Garcia-Borreguero 2013, Winkelman 2016Based on the Social anxiety disorderbData from 2 double-blind, placebo-controlled, fixed-dose studies and a relapse prevention study support the use of pregabalin in the treatment of social anxiety disorder Feltner 2011, Greist 2011, Pande 2004.Vasomotor symptoms associated with menopausebyesData from a randomized, double-blind, placebo-controlled trial support the use of pregabalin in the treatment of vasomotor symptoms (eg, hot flashes) associated with menopause, including women previously treated for breast cancer Loprinzi 2010.Based on the ContraindicationsHypersensitivity (eg, angioedema) to pregabalin or
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