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Author: Admin | 2025-04-28
Phosphodiesterase 5 inhibitors (PDE5Is) are a group of drugs used for the treatment of ED. These drugs relax Smooth muscleMuscle tissue that is responsible for the contraction of hollow organs, like blood vessels." href="https://patients.uroweb.org/glossary/smooth-muscle/" data-gt-translate-attributes="[{"attribute":"data-cmtooltip", "format":"html"}]">smooth muscle in the vessels in the PenisThe male organ for sex and urination." href="https://patients.uroweb.org/glossary/penis/" data-gt-translate-attributes="[{"attribute":"data-cmtooltip", "format":"html"}]">penis to increase blood flow. They do not cause an erection without sexual stimulation.There are 4 approved types of PDE5Is:SildenafilTadalafilVardenafilAvanafilPDE5Is are the most commonly prescribed treatment for ED. All types of PDE5Is can be equally effective. Which drug is best for you depends on how often you want to have sexual activity, and your personal experience.Because of the success of PDE5Is in treating ED, there are many fake pills on the market. These drugs are not approved for sale, they may be toxic and may damage your health. Always talk to your doctor or healthcare provider before using or buying medication for ED. Sildenafil Sildenafil is the oldest available PDE5I and is available as a pill. It comes in doses of 25, 50, and 100 mg. The dosage can be adjusted according to your needs. You can feel the effects of the drug 30-60 minutes after taking it. They may last for up to 12 hours. If you eat a fatty meal right before taking sildenafil, the drug is less effective. Interesting FactSildenafil, best known by its brand name Viagra®, is the oldest and best-known drug for ED. Although new drugs have been developed, it still accounts for more
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