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Author: Admin | 2025-04-28
HomeToradolPatient Tips Medically reviewed by Carmen Pope, BPharm. Last updated on Nov 20, 2023. How it worksUpsidesDownsidesBottom LineTipsResponse/effectivenessInteractions 1. How it works Toradol is a brand (trade) name for ketorolac which may be used to treat acute, moderately severe pain that occurs following surgery.Toradol (ketorolac) helps to relieve pain and inflammation by blocking the effects of the enzymes cyclo-oxygenase (COX)-1 and COX-2. This prevents prostaglandin synthesis (prostaglandins elevate body temperature and make nerve endings more sensitive to pain transmission). Toradol belongs to a group of medicines known as nonsteroidal anti-inflammatory drugs (NSAIDs).The Toradol brand name has been discontinued in the U.S. but generic equivalents under the name of ketorolac are still available. This patient tip is retained for information purposes only. 2. Upsides Effective for the short-term (up to five days) relief of moderate-to-severe acute pain. Usually reserved for pain that requires analgesia at the opioid level, such as that following surgery. May be used in combination with opioids for superior pain relief. Toradol tablets are usually only used as continuation therapy following IV or IM dosing of injectable ketorolac (the total duration of injectable ketorolac and oral Toradol should not exceed five days).Toradol is available as a generic under the name ketorolac. 3. Downsides If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side effects you are more likely to experience include: Dyspepsia, abdominal pain, and headache are the most common side effects. Other side effects include flatulence, dizziness, high blood pressure, sweating, rashes, tinnitus, and other gastrointestinal upsets. Stomach-related adverse effects such as bleeding, ulceration, and perforation which may be fatal are more likely to happen with Toradol than with most other NSAIDs. Older patients or those taking other medicines that affect the stomach are at a greater risk. Should not be used by people with active peptic ulcer disease or gastrointestinal bleeding. Combining with alcohol may increase the risk of stomach ulcers or bleeding. Should not be used to treat mild pain or long-standing or chronic pain. Not indicated for pediatric patients. NSAIDs (such as Toradol) have been associated with an increased risk of stroke or heart attack. The risk may be higher in patients with pre-existing conditions and at higher dosages. Avoid Toradol during or after coronary artery bypass (CABG) surgery. May affect kidney function and should not be used by people with moderate-to-severe kidney
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