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Author: Admin | 2025-04-28
Etiologic organisms of bacterial meningitis in neonates are group B streptococci, enteric gram-negative bacilli (Escherichia coli), and Listeria monocytogenes. Empiric remedy for bacterial meningitis in a neonate should embrace a combination of ampicillin and either a third- or fourth-generation cephalosporin (cefotaxime or cefepime). Empiric remedy for community-acquired bacterial meningitis in infants and youngsters ought to embrace protection for S. A third- or fourth-generation cephalosporin (ceftriaxone, cefotaxime, or cefepime) and vancomycin are really helpful as preliminary remedy for bacterial meningitis in children in whom the etiologic agent has not been recognized. Empiric therapy for community-acquired bacterial meningitis in adults (15 to 50 years of age) ought to embrace protection for S. A third-generation cephalosporin (ceftriaxone or cefotaxime) or a fourth-generation cephalosporin (cefepime) plus vancomycin is recommended for empiric remedy. Initial remedy for meningitis in postneurosurgical patients should be directed towards gram-negative bacilli, Pseudomonas aeruginosa, and Staphylococcus aureus. Ceftazidime or meropenem is beneficial for management of gram-negative bacillary meningitis in neurosurgical sufferers. Intrashunt or intraventricular vancomycin may be needed to eradicate the infection. In immunocompromised sufferers, the infecting organism could be predicted on the premise of the kind of immune abnormality. In sufferers with neutropenia, preliminary therapy for bacterial meningitis should embody protection for L. Patients with faulty humoral immunity and those that have undergone splenectomy are unable to mount an antibody response to a bacterial an infection or to control an infection attributable to encapsulated bacteria. The commonest organisms causing meningitis in the older grownup (50 years or older) are S.
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