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Author: Admin | 2025-04-28
Explore a selection of our essential drug information below, or:DescriptionA medication used in birth control for women, which is a man-made version of the natural hormone, progesterone.DescriptionA medication used in birth control for women, which is a man-made version of the natural hormone, progesterone.DrugBank IDDB00304TypeSmall MoleculeUS ApprovedYESOther ApprovedYESTherapeutic CategoriesProgestins Mechanism of ActionProgesterone receptorAgonistEstrogen receptorAgonistSummaryDesogestrel is a synthetic progestin used in contraception, often in combination with ethinyl estradiol.Brand NamesApri 28 Day, Azurette 28 Day, Bekyree 28 Day, Caziant 28 Day, Cesia 28 Day, Cyred 28 Day, Emoquette, Enskyce 28 Day, Freya, Isibloom 28 Day, Juleber 28 Day, Kalliga, Kariva 28 Day, Linessa, Marvelon, Pimtrea Pack, Reclipsen, Simliya, Velivet 28 Day, Viorele 28 Day, Volnea 28 DayGeneric NameDesogestrelDrugBank Accession NumberDB00304BackgroundDesogestrel, a prodrug, is a third generation progestogen1 and hence, a member of the gonane family which was largely used in Europe before being approved in the US and Canada.4 It was firstly generated from a study that showed that 11-beta and 11-alkylidene substituent in nortestosterone can enhance the biological activity.10 Desogestrel is now produced semi-synthetically from naturally occurred plant steroids.14 In the US, desogestrel is found only in combination with ethinyl estradiol.5 The first approved drug containing desogestrel was developed by Organon USA Inc in 1972 and FDA approved in 1992.11TypeSmall MoleculeGroupsApprovedStructureWeightAverage: 310.473 Monoisotopic: 310.229665582 Chemical FormulaC22H30OSynonyms13-Ethyl-11-methylene-18,19-dinor-17α-pregn-4-en-20-yn-17-olDesogestrelDésogestrelDesogestrelumExternal IDs ORG 2969ORG-2969IndicationOral desogestrel is used in combination with ethinylestradiol as a contraceptive agent for the prevention of pregnancy.LabelDesogestrel is part of the combined oral contraceptives that contain a mix of estrogen and progestin which
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