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Author: Admin | 2025-04-28
Most of our educational content addresses how to use psychedelics intentionally—and this typically means using a single psychoactive substance at a time. However, many people are curious about the effects of mixing cannabis with psychedelics. Now without further ado, here is our definitive guide to mixing cannabis and psychedelics. Below we’ll cover what happens when you combine these substances, whether it’s effective to mix the two, and how to do so safely. What class of drugs does cannabis fall into?First of all, it’s important to note that cannabis is unique in that it doesn’t clearly fit into a particular category of drugs—it’s not an opioid, a depressant, or a stimulant. We maintain the view that it’s most appropriately categorized as a psychedelic due to its psychoactive properties.However, cannabis and psychedelics activate via different methods; cannabis relies on the endocannabinoid system, whereas psychedelics usually affect key hormones and chemical neurotransmitters such as serotonin, dopamine, and cortisol. One thing is clear, cannabis is a rather mysterious drug in that it affects each user differently. Plus when you consider the myriad of different strains—we’re talking about millions of different perceived effects produced by the same species of plant.So why is this important? Because the interaction of cannabis and psychedelics isn’t so simple. The more familiar you are with how your body responds to cannabis, the easier it will be to combine the two. The less familiar you are with how cannabis interacts with your body, the more variables you’ll need to manage.Is it safe to combine cannabis and psychedelics?Yes! THC is physiologically safe to combine with psychedelics, but it’s important to note that it can result in psychological challenges due to its propensity to increase the intensity, anxiety, and duration of the psychedelic substance it’s being combined with. More on this below.What happens when combining cannabis and psychedelics?It’s important to differentiate between high-THC and high-CBD strains of cannabis. THC generally makes the experience more intense, while simultaneously prolonging the duration of psychedelic effects. We often meet with clients who have consumed a psychedelic substance like magic mushrooms and think they are coming down
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